該雜志邀請評論關(guān)于化學(xué)物質(zhì)與生物系統(tǒng)相互作用的原始論文。藥理學(xué)和治療學(xué)的所有方面都是適當(dāng)?shù)?，但是沒有劑量反應(yīng)或機制研究的描述性病例報告是不能接受的。只有在提供數(shù)據(jù)表明使用新方法獲得了新的或更可靠的藥理信息時，才會審查主要涉及新方法的手稿。

The Journal invites for review original papers dealing with interactions of chemicals with biological systems. All aspects of pharmacology and therapeutics are appropriate, but descriptive case reports without dose-response or mechanistic studies are not acceptable. Manuscripts dealing primarily with new methods will be reviewed only if data are presented showing that new or more reliable pharmacological information has been obtained with their use.